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Albert Einstein College of Medicine Zebrafish Core

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Bronx, New York, US

About Albert Einstein College of Medicine Zebrafish Core

Zebrafish is a powerful system for studies of embryogenesis and to investigate mechanisms underlying human diseases. The zebrafish is particularly well suited to study complex and acquired diseases and to identify new disease genes owing to its genetic tractability, transparency of the organism, and the ease of... Show more »

Zebrafish is a powerful system for studies of embryogenesis and to investigate mechanisms underlying human diseases. The zebrafish is particularly well suited to study complex and acquired diseases and to identify new disease genes owing to its genetic tractability, transparency of the organism, and the ease of conducting chemical screens to identify diagnostic and potential therapeutic targets. Moreover, the high degree of genetic conservation renders translation between fish and mammals a possibility. For example, this model system can be used to validate and characterize genome-wide association study (GWAS) candidates through gain of function and loss of function approaches. For loss of function analysis the candidate, the gene of interest can be transiently knocked down or stable mutant alleles can be generated through reverse genetic mutagenesis approaches. The phenotypes produced by the normal and mutant versions can provide an indication of the gene’s function in development and disease. The Einstein Zebrafish Core was established to facilitate this type of analysis.

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Our Services (7)


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Zebrafish Models

Price on request
  • 100 fertilized wild type embryos
  • 50 fixed embryos suitable for RNA in situ hybridization or immunohistological analysis
  • Fish Fin Clip + Genotyping (per 50 fish and more than 200 fish)
  • Fish Fin Clip + Genotyping (per 50 fish and up to 200 fish)
  • Fish Fin Clips (per 100)
  • Fish Fin Clips (per 50)
  • Genotyping (per... Show more »
  • 100 fertilized wild type embryos
  • 50 fixed embryos suitable for RNA in situ hybridization or immunohistological analysis
  • Fish Fin Clip + Genotyping (per 50 fish and more than 200 fish)
  • Fish Fin Clip + Genotyping (per 50 fish and up to 200 fish)
  • Fish Fin Clips (per 100)
  • Fish Fin Clips (per 50)
  • Genotyping (per 100)
  • Genotyping (per 50)
  • Husbandry
  • Import a mutant fish line
  • Maintain Fish Line
  • Microinjection service
  • Microinjection training
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Zebrafish Transgenic Services

Price on request
Request a quote for more information about this service.

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Genetic Engineering

Price on request

Genetic Engineering Services

Genetic Engineering Services

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Fish, Reptile, and Amphibian Models

Price on request

Fish, Reptile, and Amphibian Models Services

Fish, Reptile, and Amphibian Models Services

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Model Organisms

Price on request

Model Organisms Services

Model Organisms Services

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Animal Models and Studies

Price on request

Animal Models and Studies Services

Animal Models and Studies Services

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Biology

Price on request

Biology Services

Biology Services

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Clinton DePaolo

Director of Zebrafish Core Services

Albert Einstein College of Medicine Zebrafish Core has not received any reviews.

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