Advaita Bioinformatics

Advaita develops bioinformatics data analysis tools with capabilities to integrate multi-'omic' data from a systems biology perspective. Our proprietary computational method, Impact Analysis, considers the type, function, position and interaction between genes in a pathway as opposed to other approaches that consider genes to be independent. Through our $2.2 million NIH STTR Phase II award, we have developed a software platform called Pathway-Guide for the analysis of data from high-throughput microarray and next-generation sequencing experiments. Our next generation product, iPathwayGuide, is a web-based pathway analysis application based on our Impact Analysis method. We are the only company in the industry that includes other crucial factors about the genes in addition to classical statistics. iPathwayGuide includes unique capabilities such modeling SNPs, miRNAs and drugs directly on the pathways and predicting miRNA potentially regulating gene expression in your samples based only on mRNA data. Our vision is to create a platform for multi-omic integration and analysis from a systems biology level. Advaita is also working on developing innovative tools for subtyping of diseases and patients. These tools address the classic "responder" vs. "non-responder" problem facing 50% of drugs that reach Phase 3 clinical trials. With our technology, we can identify truly homogeneous populations and the mechanisms that distinguish them from other populations.