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ACROBiosystems

2 Orders Completed
Wilmington, Delaware, US

About ACROBiosystems

Type: Partnership Size: 51-200 employees

** ACROBiosystems offers SARS-CoV-2 protein antigens, antibodies, kits, and other related products to facilitate the development of serologic tests, therapeutic antibodies, and vaccines. Submit a quote request containing the word ‘COVID-19’ to receive even more details.


ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics, vaccines, and diagnostics. We have established long-term collaborations with big pharma like Pfizer, Novartis, and Johnson & Johnson, and well-known academic institutes.


To fight against COVID 19, ACROBiosystems has been keeping a close eye on the continuing pandemic and are accelerating the development of SARS-CoV-2 protein antigens, antibodies, kits, and other related products to facilitate the development of serologic tests, therapeutic antibodies, and vaccines.
As the viruses is constantly mutating, new variants are expected to potential increase transmissibility and severity of COVID-19. ACROBiosystems is going full steam ahead on developing a collection of recombinant antigens for these emerging variants. The reagents can rapidly assess the efficacy of existing therapeutics and vaccines against the variants and enable development of mutation resistant antibodies and vaccine candidates/booster shots. We would like to share the good news with you that ACROBiosystems has recently launched a ready-to-use neutralizing antibody titer serologic assay kit (Cat.No. TAS-K022) which can sensitively and specifically detect COVID 19 neutralizing antibodies within 2 hours. The kit performance shows high correlation with FDA-EUA approved ELISA kit!
We believe our SARS-CoV-2 related products can greatly save the researchers’ time and make the research on SARS-CoV-2 easier.
A glance of our hot products:
• Spike mutants for the emerging variants of SARS-COV-2 • Neutralizing antibody titer serologic assay kit • Immune Checkpoint Proteins • Bispecific antibodies • Antibody drug conjugates • Cell therapies • Fc Receptor SPR /BLI analytical service

Download recently published eBook: A year later: What we know about SARS-CoV-2 infectivity and growing concerns of emerging variants.

Our Services (8)


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Recombinant Protein Expression

Price on request

Custom Recombinant Protein expression utilizing HEK 293. Priced based on target and quantity


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Bispecific Antibody Analysis

Price on request

Antigen BInding Assay for BiSpecific Ab

High-throughput process for screening highly cytotoxic bispecific antibodies was conducted without purification stage.

Tag-sandwich ELISA with tandemly-arranged peptide tags enabled to determine the recombinant antibodies in crude condition.

Surface plasmon resonance approach with the tag-sandwich ELISA supplied qualitative binding affinity from crude samples.


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MSD Assays

Price on request

ACROBiosystems offers an array of MSD-based immunoassays with a proven increase in both dynamic range and sensitivity, made possible through electro chemiluminescent labeling. ACROBiosystems utilizes our expertise to accurately access clients’ needs and to guide in the design of assays more sensitive than traditional ELISA. MSD assays exhibit a reduced need to repeat samples that are above the ULOQ and the electro chemiluminescence detection technology reduces background signals by separating the excitation mechanism from the signal.
In our efforts to provide the right blend of innovation and value to our clients, ACROBiosystems scientists have implemented mastered numerous assay platforms over the years. Our recent introduction of the MSD SQ120 into our assay development portfolio is an extension of that progress. This technology can be applied to all types of traditional ELISAs, such as direct, indirect, sandwich or competitive assays at an increased sensitivity level that can detect samples with concentrations as low as 0.1pg/mL. Let us show you how increased sensitivity and reduced sample requirements can open new possibilities in your studies.


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Assay Development

Price on request

ACROBiosystems specializes in development of various Assays.
Cell Based
ELISA
NAB
ADA


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TCR Repertoire Analysis

T-Cell Receptor Repertoire Analysis
Price on request

Human TCR Bulk Cell Profiling

TCR Screening Assay

Assay for Full Length Reads of V(D)J Regions
• Unbiased gene amplification using 5’RACE with 2 rounds of semi-nested PCR approach.
• Incorporation of unique tags for PCR correction.
• Full-length V(D)J library generation.
Sample Requirements: 10 ng–3 µg of RNA obtained from peripheral blood, or from 50–10,000 purified T cells


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PCR

Price on request

ACROBiosystems offers a comprehensive set of real time PCR services (also referred to as quantitative PCR services or qPCR services), including gene expression, miRNA expression, SNP genotyping, copy number variation, and absolute quantification.  Real-time PCR (qPCR) is the most widely used technology for nucleic acid quantification and genotyping.  High-quality data with high reproducibility and unmatched dynamic range can be generated with ease due to optimized chemistry, instrumentation, and analysis software.


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Antibody Services

Price on request

Antibody Services


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BCR Sequencing

Price on request

ACROBiosystems utilizes the Illumina MiSeq. The 5’-RACE method reduces variability and allows for priming from the constant region of BCR heavy or light chains. This kit combines these benefits with gene-specific amplification to capture complete V(D)J variable regions of BCR transcripts and provide a highly sensitive and reproducible method for profiling B-cell repertoires. Downstream sequencing of H/K/L chains allows for accurate identification of top clonotypes and reliable assignment of isotype in a majority of cases. Sample Requirements: 10 ng–3 µg of total RNA from spleen, lymph node, PBMCs, and hybridomas.


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Stella Si

Business Development Manager

FileType/PDF Created with Sketch. 01 Checkpoint Proteins_Brochure_20190708.pdf

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FileType/PDF Created with Sketch. 03 ADA Brochure_20181205.pdf

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FileType/PDF Created with Sketch. ACROBiosystems_A year later_ What we know about SARS-CoV-2 infectivity and growing concerns of emerging variants_202102.pdf

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FileType/PDF Created with Sketch. ACROBiosystems_Neutralizing antibody titer kit_EN_202102.pdf

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FileType/PDF Created with Sketch. ACROBiosystems_Recombinant Spike Protein Trimer_ more powerful than you think_202101.pdf

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FileType/PDF Created with Sketch. CD3 Proteins-Hot target for bispecific antibody.pdf

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FileType/PDF Created with Sketch. Critical reagents for vaccine development_ACROBiosystems_EN_202010.pdf

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FileType/PDF Created with Sketch. Hot Targets of CAR-T Cell Therapy.pdf

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