** ACROBiosystems offers SARS-CoV-2 protein antigens, antibodies, kits, and other related products to facilitate the development of serologic tests, therapeutic antibodies, and vaccines. Submit a quote request containing the word ‘COVID-19’ to receive even more details.
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics, vaccines, and diagnostics. We have established long-term collaborations with big pharma like Pfizer, Novartis, and Johnson & Johnson, and well-known academic institutes.
To fight against COVID 19, ACROBiosystems has been keeping a close eye on the continuing pandemic and are accelerating the development of SARS-CoV-2 protein antigens, antibodies, kits, and other related products to facilitate the development of serologic tests, therapeutic antibodies, and vaccines.
Custom Recombinant Protein expression utilizing HEK 293. Priced based on target and quantity
Antigen BInding Assay for BiSpecific Ab
High-throughput process for screening highly cytotoxic bispecific antibodies was conducted without purification stage.
Tag-sandwich ELISA with tandemly-arranged peptide tags enabled to determine the recombinant antibodies in crude condition.
Surface plasmon resonance approach with the tag-sandwich ELISA supplied qualitative binding affinity from crude samples.
ACROBiosystems offers an array of MSD-based immunoassays with a proven increase in both dynamic range and sensitivity, made possible through electro chemiluminescent labeling. ACROBiosystems utilizes our expertise to accurately access clients’ needs and to guide in the design of assays more sensitive than traditional ELISA. MSD assays exhibit a reduced need to repeat samples that are above the ULOQ and the electro chemiluminescence detection technology reduces background signals by separating the excitation mechanism from the signal.
In our efforts to provide the right blend of innovation and value to our clients, ACROBiosystems scientists have implemented mastered numerous assay platforms over the years. Our recent introduction of the MSD SQ120 into our assay development portfolio is an extension of that progress. This technology can be applied to all types of traditional ELISAs, such as direct, indirect, sandwich or competitive assays at an increased sensitivity level that can detect samples with concentrations as low as 0.1pg/mL. Let us show you how increased sensitivity and reduced sample requirements can open new possibilities in your studies.
ACROBiosystems specializes in development of various Assays.
Human TCR Bulk Cell Profiling
TCR Screening Assay
Assay for Full Length Reads of V(D)J Regions
• Unbiased gene amplification using 5’RACE with 2 rounds of semi-nested PCR approach.
• Incorporation of unique tags for PCR correction.
• Full-length V(D)J library generation.
Sample Requirements: 10 ng–3 µg of RNA obtained from peripheral blood, or from 50–10,000 purified T cells
ACROBiosystems offers a comprehensive set of real time PCR services (also referred to as quantitative PCR services or qPCR services), including gene expression, miRNA expression, SNP genotyping, copy number variation, and absolute quantification. Real-time PCR (qPCR) is the most widely used technology for nucleic acid quantification and genotyping. High-quality data with high reproducibility and unmatched dynamic range can be generated with ease due to optimized chemistry, instrumentation, and analysis software.
ACROBiosystems utilizes the Illumina MiSeq. The 5’-RACE method reduces variability and allows for priming from the constant region of BCR heavy or light chains. This kit combines these benefits with gene-specific amplification to capture complete V(D)J variable regions of BCR transcripts and provide a highly sensitive and reproducible method for profiling B-cell repertoires. Downstream sequencing of H/K/L chains allows for accurate identification of top clonotypes and reliable assignment of isotype in a majority of cases. Sample Requirements: 10 ng–3 µg of total RNA from spleen, lymph node, PBMCs, and hybridomas.
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