Accelevir Diagnostics is a Maryland biotechnology company that spun out of Johns Hopkins Medicine to develop and commercialize new tools for the field of HIV-1 persistence and eradication.
We are developing a complementary suite of assays that measure key analytes of viral persistence, including: intact proviral DNA, total proviral DNA, cell-associated HIV-1 RNA, and replication-competent latent proviruses.
Cell-associated HIV-1 mRNA
RT-qPCR assay for measuring amount of cell-associated HIV-1 mRNA per million CD4+ T cells from HIV-1 infected individuals.
Quantitative multiplex molecular assay that distinguishes and separately quantifies the frequency of intact, defective, and total proviruses in samples from HIV-1 infected individuals.
Quantitative viral outgrowth assay (QVOA) measuring the frequency of latent, replication-competent HIV-1 induced per million input CD4+ T cells from infected individuals.
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