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Acanthus Research Inc.

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Mississauga, Ontario, CA

About Acanthus Research Inc.

Acanthus Research Inc., established in 2008, is a manufacturer and worldwide distributor of pharmaceutical reference standards. All our materials come fully characterized for identity (1H NMR, 13C NMR, 2D NMR, HRMS) and purity (HPLC), ready to use for quantitation. Our state of the art analytical laboratories... Show more »

Acanthus Research Inc., established in 2008, is a manufacturer and worldwide distributor of pharmaceutical reference standards. All our materials come fully characterized for identity (1H NMR, 13C NMR, 2D NMR, HRMS) and purity (HPLC), ready to use for quantitation. Our state of the art analytical laboratories ensure high quality of all our materials. Our synthetic laboratories can handle any type of projects, from mg to multi-gram scale.

We have expertise in stable-isotope labeling (2H, 13C, 15N) of reference materials for bioanalytical use: labeled drugs and metabolites. We have lots of experience in synthesis of glucuronides, sulfates, N-oxides, and hydrolytic products.

We perform fate and purge studies for impurities in new chemical processes, isolation and characterization of process impurities, analytical method development.

Our dedicated team of experienced scientists will ensure that your needs for reference materials will be taken care of with speed while guaranteeing top quality and excellence in customer service.

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Our Services (33)


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Chemical Reference Standards

Price on request

We manufacture and certify analytical standards of drug substances at any developmental stage. This includes identification, synthesis or isolation of process impurities, degradation products, metabolites and stable isotope labeled analogs for use as internal standards in bioanalysis.

We manufacture and certify analytical standards of drug substances at any developmental stage. This includes identification, synthesis or isolation of process impurities, degradation products, metabolites and stable isotope labeled analogs for use as internal standards in bioanalysis.

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Chemical Synthesis

Price on request

We offer custom synthesis services of up to gram-quantities of materials for a wide range of industrial and academic customers.

We always respond quickly to inquiries. We listen to our customers and provide products that meet their specifications.

The purity of our products is supported by solid analytical data and their certification is tailored to our customer needs.

We offer custom synthesis services of up to gram-quantities of materials for a wide range of industrial and academic customers.

We always respond quickly to inquiries. We listen to our customers and provide products that meet their specifications.

The purity of our products is supported by solid analytical data and their certification is tailored to our customer needs.

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gram milligram

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Metabolite Generation

Price on request

We specialize in chemical synthesis of metabolites of active pharmaceutical ingredients and their stable isotope labeled analogs (deuterium, carbon-13, nitrogen-15): glucuronides, sulfates, oxides, hydroxylated species, hydrolytic metabolites etc. From mg quantities to hundred mg quantities.

We specialize in developing stable... Show more »

We specialize in chemical synthesis of metabolites of active pharmaceutical ingredients and their stable isotope labeled analogs (deuterium, carbon-13, nitrogen-15): glucuronides, sulfates, oxides, hydroxylated species, hydrolytic metabolites etc. From mg quantities to hundred mg quantities.

We specialize in developing stable isotope labeling strategies for new molecular entities and their relevant metabolites.

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Deuterium

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Process Consulting

Price on request

We offer studies for your process development projects, such as fate and purge studies for impurities, optimization of individual chemical steps, investigation of synthetic routes, isolation or synthesis and characterization of reference standards for your process impurities and intermediates, up to multi gram quantities,... Show more »

We offer studies for your process development projects, such as fate and purge studies for impurities, optimization of individual chemical steps, investigation of synthetic routes, isolation or synthesis and characterization of reference standards for your process impurities and intermediates, up to multi gram quantities, run-through of the whole synthesis with isolation of all relevant impurities. We develop analytical methods for testing of your intermediates, products, or in-process samples.

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Pharmaceutical Manufacturing

Price on request

Laboratory scale non-GMP batch production for non-GLP studies. Up to 500 g scale.

Laboratory scale non-GMP batch production for non-GLP studies. Up to 500 g scale.

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Chemistry, Manufacturing and Controls (CMC)

Price on request

Evaluation of chemical processes for the risk of potentially genotoxic impurities in the final product, developing control strategies, fate and purge studies for process impurities, developing strategies for control of elemental impurities as per the current guidelines.

Evaluation of chemical processes for the risk of potentially genotoxic impurities in the final product, developing control strategies, fate and purge studies for process impurities, developing strategies for control of elemental impurities as per the current guidelines.

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Analytical Method Development

Price on request

Our state of the art analytical laboratory can develop reliable analytical methods for impurity quantitation in API intermediates, API's and finished dosage (stability indicating). We can support the analytical development with the in-house development of reference materials in our synthetic laboratories.

Our state of the art analytical laboratory can develop reliable analytical methods for impurity quantitation in API intermediates, API's and finished dosage (stability indicating). We can support the analytical development with the in-house development of reference materials in our synthetic laboratories.

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Synthetic Chemistry

Price on request
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Impurity Separation

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Manufacturing Services

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Separation/Purification Services

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Biology

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Metabolomics

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Formulation Services

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Project Management

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Assay Development

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Chemistry and Materials

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Analytical Chemistry Services

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Biochemistry & Molecular Biology

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In vivo Protein Binding Assays

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Chromatography

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Drug Discovery

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Drug Discovery & Development

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Chemicals

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Medicinal Chemistry

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Contract Research

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HPLC

High Performance Liquid Chromatography
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Custom Manufacturing

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Medicinal Chemistry

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Contract Services Directory

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R&D Services

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Biomolecular Interaction Analysis

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Liquid Chromatography (LC)

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Stefan Wodzinski

Director, Business Development
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Newsletter October 2017.pdf

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