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Abveris, Inc

13 Orders Completed
Stoughton, Massachusetts, US

About Abveris, Inc

**Abveris offers services and/or reagents specific to COVID-19 research. Submit a quote request containing the word ‘COVID-19’ to receive more details.**


Abveris is a premium contract research organization that uses genetically engineered in vivo systems for the discovery of antibodies in tight timelines. Our discovery platform is anchored on an proprietary uses proprietary mice, Diversimab, that have been engineered to express a more diverse antibody repertoire than wild-type mice. The limiting factor in most in-vivo antibody discovery platforms is the diversity of the immune response of the host animal. We deliver antibodies to targets, and individual epitopes on those targets, that cannot be found in natural in vivo systems. This enables the discovery of antibodies with specificities that cannot be found in other in-vivo systems. To streamline antibody screening from upstream hit generation, a wide range of screening methods and assay development capabilities have been developed in-house in Abveris. When well-designed screening methods are applied to the large panel of hybridomas discovered, optimal antibodies are delivered. Abveris’s platform can deliver antibody candidates with desired affinity, specificity, and epitopic coverage in industry-leading timelines.


Abveris's offering is differentiated in the followings:

  1. World-leading, proprietary immunization expertise that can break tolerance and generate superb immune response against challenging targets (such as cell surface target including GPCR), as well as antibody repertoire based on Diversimab and other humanized mice from Harbour, Alloy, and Trianni.
  2. Optimized, function-forward hybridoma system that allows accelerate the timeline for delivery of monoclonal hybridoma cell lines in only 60 days.
  3. Single B cell screening using the Beacon® platform to expedite delivery of antibody sequence from immunization as quick as 29 days.

Our Services (23)


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Epitope Mapping

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Recombinant Protein Expression

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Antibody Production by DNA Immunization

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Hybridoma Sequencing

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Hybridoma Subcloning

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Monoclonal Antibody (mAb) Development

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B Cell Count

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ELISA

Enzyme-linked immunosorbent assay
Price on request

ELISA for primary antibody hit screening


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Flow Cytometry

Price on request

Intellicyt System for high-throughput FACS analysis


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Biolayer Interferometry

Price on request

Octet System by Forte Bio - Affinity Ranking


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Assay Development

Price on request

Assay development for antibody hit generation


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Surface Plasmon Resonance (SPR)

Price on request

Carterra System - Affinity Ranking


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Antibody Discovery

Price on request

Royalty/milestone free, rapid delivery and you can expect antibodies to novel epitopes.


Single B Cell Screening

Using an in-house developed and optimized Single B Cell Screening Workflow based on Berkeley Lights' Beacon system for rapid antibody discovery.


Plasma B Cell Screening


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Anti-Idiotype Antibody Production

Price on request
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Monoclonal Antibody (mAb) Production

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Panels of custom-screened mAbs delivered against a wide variety of target types. Difficult targets are welcome.


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Biochemistry & Molecular Biology

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Therapeutic Monoclonal Antibody (mAb) Development

Price on request

Industry-leading sequence-to-sequence delivery timeline


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Antibody Services

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Protein Services

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Biomolecular Interaction Analysis

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Biomolecular Interaction Analysis Services


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Hybridoma Screening

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Hybridoma Fusion

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Animal Immunization for Antibody Production

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Garren Hilow

Director of Business Development, Co-Founder
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Ryan Kelly

Business Development
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