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Abpro Bioresearch

Woburn, Massachusetts, US

Abpro Bioresearch provides early stage non-GLP preclinical studies to assess drug candidates during early product development process. We are flexible and responsive, providing customized studies to suit each study objectives. With our diverse expertise and comprehensive experience, we offer a range of animal models in rodents for pharmacology & toxicology studies as well as in vitro studies which can be stand alone or in support of in vivo studies.

Abpro Bioresearch has not listed any services.

In vivo Drug Efficacy Testing
Price on request

Whether you are assessing small molecule drug candidate efficacy in a human xenograft tumor mouse model, or evaluation of immune-based therapies in a syngeneic mouse tumor model, Abpro BIoresearch provides you with the expertise in a wide variety of models and dosing routes and regimens to suit your needs. Efficacy as measured by... Show more »

Whether you are assessing small molecule drug candidate efficacy in a human xenograft tumor mouse model, or evaluation of immune-based therapies in a syngeneic mouse tumor model, Abpro BIoresearch provides you with the expertise in a wide variety of models and dosing routes and regimens to suit your needs. Efficacy as measured by tumor growth kinetics can be combined with pharmacokinetics, clinical pathology, histopathology and local/systemic immune function profiling in the following models:

  • Xenograft tumor models
  • Syngeneic mouse tumor models
  • PDX models
  • Custom models upon request
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Flow cytometry
Melanoma
xenograft
Colorectal cancer
Syngeneic tumor model
Orthotopic tumor xenograft model
Prostate Cancer
Breast cancer
Lung Cancer
Ovarian Cancer
Gastric Cancer
Pancreatic cancer
Liver cancer
Bladder cancer
PDX
in vivo imaging
In vivo Toxicity Testing
Price on request

Abpro offers a full range of in vivo non-GLP toxicology services in both mice and rats providing early assessment of drug candidate toxicity allowing for a more informed drug discovery direction and more confident decision-making. Examples of our toxicology study capabilities include:

Abpro offers a full range of in vivo non-GLP toxicology services in both mice and rats providing early assessment of drug candidate toxicity allowing for a more informed drug discovery direction and more confident decision-making. Examples of our toxicology study capabilities include:

  • Toxicokinetics
  • Maximum tolerated dose estimation (fixed or up and down dosing schedule)
  • Acute toxicity (up to 14 days)
  • Single or repeated dose
  • NOEL/NOAEL
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Repeated dose Toxicology 14, 28, 90 days
Toxicology
MTD
dose range finding
Single dose toxicology
In vivo PK/PD Studies
Price on request

with noncompartmental and compartmental analysis

Abpro offers in vivo preclinical pharmacology services in both mouse and rat using a full range of dosing administration routes and regimens for both small molecules and biologics. Tissue and body fluid samples can either be shipped to the sponsor or undergo bioanalysis at Abpro.

with noncompartmental and compartmental analysis

Abpro offers in vivo preclinical pharmacology services in both mouse and rat using a full range of dosing administration routes and regimens for both small molecules and biologics. Tissue and body fluid samples can either be shipped to the sponsor or undergo bioanalysis at Abpro.

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PK/PD
in vivo PK
Human Tumor Xenograft Models
Price on request
Request a quote for more information about this service.
Multiple Myeloma
Melanoma
Breast cancer
Lung Cancer
Ovarian Cancer
Pancreatic cancer
Liver cancer
Lymphoma
Mesothelioma
Neuroblastoma
Colon cancer
Leukemia
Syngeneic (Allograft) Tumor Models
Price on request
Request a quote for more information about this service.
Melanoma
Sarcoma
Colorectal cancer
Breast cancer
Lung Cancer
Pancreatic cancer
Liver cancer
Lymphoma
Renal Cancer
Leukemia
Metabolic Disease Animal Models
Price on request

Choosing the most appropriate model for your metabolic disease research and drug development projects is crucial for proper efficacy assessment of therapeutic interventions. At Abpro, we can work with you to choose the most appropriate model for your disease area from a wide array of genetic or (diet or drug) induced disease... Show more »

Choosing the most appropriate model for your metabolic disease research and drug development projects is crucial for proper efficacy assessment of therapeutic interventions. At Abpro, we can work with you to choose the most appropriate model for your disease area from a wide array of genetic or (diet or drug) induced disease models. Examples include:

  • Type I and II diabetes models
  • Nutritional and genetic obesity models
  • Dyslipidemia
  • Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)
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Autoimmune Disease Animal Models
Price on request

With the wide range of rodent autoimmune and inflammatory models of human disease it can be confusing to decide which model is best for your particular drug development and research needs. Our immunology scientists have the knowledge and experience to help you design the most appropriate studies for your goals. We can provide you... Show more »

With the wide range of rodent autoimmune and inflammatory models of human disease it can be confusing to decide which model is best for your particular drug development and research needs. Our immunology scientists have the knowledge and experience to help you design the most appropriate studies for your goals. We can provide you a comprehensive qualitative and quantitative assessment of immune cell populations and functional readouts. Examples of our disease models include:

  • Systemic Lupus Erythematosus (SLE)
  • Multiple Sclerosis
  • Type 1 diabetes
  • Psoriasis
  • Inflammatory Bowel Disease
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In vitro Antibody-Drug Conjugate Toxicity Testing
Price on request
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ADME/DMPK Studies
Drug Metabolism and Pharmacokinetics
Price on request
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Custom Cell-Based Assay Development
Price on request

Abpro has a highly talented team of immunoassay scientists with extensive assay development experience. Our team has delivered high quality, functional monoclonal antibodies and corresponding assays to traditionally difficult targets (e.g., GPCRs, high homology proteins, idiotypes). Our expertise includes, but is not limited to:... Show more »

Abpro has a highly talented team of immunoassay scientists with extensive assay development experience. Our team has delivered high quality, functional monoclonal antibodies and corresponding assays to traditionally difficult targets (e.g., GPCRs, high homology proteins, idiotypes). Our expertise includes, but is not limited to: sandwich ELISAs for diagnostic kit development, competition, neutralizing, and blocking assays for drug screening and development.

In addition to assay development, we also have high throughput screening capabilities. Our platform leverages state-of-the-art automation to process and screen a huge volume of samples accurately and efficiently. Our screening capabilities include:

  • ELISA
  • Affinity Ranking (ForteBio Octet™)
  • Western Blots
  • Flow Cytometry
  • Immunoprecipitation
  • Dot Blot

Assay development and high throughput screening can be included as part of a custom antibody development project or offered as an independent service.

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Pharmacology & Toxicology
Price on request
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Biochemistry & Molecular Biology
Price on request
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Drug Discovery & Development
Price on request

Drug Discovery & Development Services

Drug Discovery & Development Services

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Custom Mouse Models
Price on request

Oncology Animal Models Services - Xenograft, syngeneic, PDX
Also offer a wide array of genetic or induced disease models such as Type I and II diabetes models, inflammatory bowel disease

Oncology Animal Models Services - Xenograft, syngeneic, PDX
Also offer a wide array of genetic or induced disease models such as Type I and II diabetes models, inflammatory bowel disease

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Mouse
Rat
In vitro Toxicity Testing
Price on request

In vitro Toxicity Testing Services

In vitro Toxicity Testing Services

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Oncology Animal Models
Price on request

Oncology Animal Models Services

Oncology Animal Models Services

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Rodent Models
Price on request

Rodent Models Services

Rodent Models Services

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