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AbovChem LLC

35 Orders Completed
San Diego, California, US

About AbovChem LLC

We are locally owned and operated in sunny San Diego, California. Our mission is to help you identify your next clinical candidates as soon as possible. To achieve that, our strategy is two-fold: 1. Supply you with the most drug-like medicinal chemistry building blocks, and 2. Have all our products in stock... Show more ยป

We are locally owned and operated in sunny San Diego, California. Our mission is to help you identify your next clinical candidates as soon as possible. To achieve that, our strategy is two-fold: 1. Supply you with the most drug-like medicinal chemistry building blocks, and 2. Have all our products in stock 100% of the time so we get them in your hands as fast as possible. We also strive to do our part to keep our environment clean, and help build a sustainable biotech innovation ecosystem. On the environmental protection side, we take a minimalist approach in packaging, and limit our stock to room-temperature-stable products only to reduce energy cost in storage.

Selected Publications

  • Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115 J. Med. Chem. 2015, 58, 5599.
  • Discovery of Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor CC-223 J. Med. Chem. 2015, 58, 5323.
  • Use of core modification in the discovery of CC214-2, an orally available, selective inhibitor of mTOR kinase Bioorg. Med. Chem. Lett. 2013, 23, 1588.
  • Discovery and SAR exploration of a novel series of imidazo[4,5-b]pyrazin-2-ones as potent and selective mTOR kinase inhibitors Bioorg. Med. Chem. Lett. 2011, 21, 6793.
  • Methods of synthesis and purification of heteroaryl compounds, WO2011/053518.
  • mTor kinase inhibitors for oncology indications and diseases associated with the mTor/PI3K/Akt pathway, WO2010/062571.
  • Aminotriazolopyridines and their use as kinase inhibitors, WO2010/027500.
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Our Services (6)


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Synthetic Building Blocks and Intermediates

Price on request

Chemical building blocks (~8,000) for medicinal chemistry.

Chemical building blocks (~8,000) for medicinal chemistry.

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Chemical Reference Standards

Price on request

Reference Tool Compounds (~6,000) for target validation.

Reference Tool Compounds (~6,000) for target validation.

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Chemical Synthesis

Price on request

Custom synthesis of chemical probes, reference tool compounds, and focus libraries.

Custom synthesis of chemical probes, reference tool compounds, and focus libraries.

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Synthetic Chemistry

Price on request
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Analytical Chemistry Services

Price on request
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Chemistry and Materials

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Branden Lee

Business Development

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  • Positive review for Chemical Synthesis:

    September 2018

    "Working with Branden has been a great experience. He is very knowledgeable about synthesis of custom materials, formulating and purification of organics. He is a clear communicator and sends detailed updates with progress reports and creative solutions to any road blocks that may be causing delays. I'd definitely work with Branden again."

  • Positive review for Chemical Synthesis:

    March 2018

    "I'm very satisfied with the quality of the compound AbovChem synthesized for us and their reasonable price for the service."

  • Positive review for Chemical Synthesis:

    March 2017

    "AbovChem, specifically Branden Lee, have been very flexible and have actively worked with us when we have needed to change the scope. The turnaround time for responses and proposals has been extremely rapir, usually within 1-2 hours."

AbovChem LLC has not received any endorsements.