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AbovChem LLC

San Diego, California, US

We are locally owned and operated in sunny San Diego, California. Our mission is to help you identify your next clinical candidates as soon as possible. To achieve that, our strategy is two-fold: 1. Supply you with the most drug-like medicinal chemistry building blocks, and 2. Have all our products in stock 100% of the time so we get them in your hands as fast as possible. We also strive to do our part to keep our environment clean, and help build a sustainable biotech innovation ecosystem. On the environmental protection side, we take a minimalist approach in packaging, and limit our stock to room-temperature-stable products only to reduce energy cost in storage.

Selected Publications

  • Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115 J. Med. Chem. 2015, 58, 5599.
  • Discovery of Mammalian Target of Rapamycin (mTOR)... Show more »

We are locally owned and operated in sunny San Diego, California. Our mission is to help you identify your next clinical candidates as soon as possible. To achieve that, our strategy is two-fold: 1. Supply you with the most drug-like medicinal chemistry building blocks, and 2. Have all our products in stock 100% of the time so we get them in your hands as fast as possible. We also strive to do our part to keep our environment clean, and help build a sustainable biotech innovation ecosystem. On the environmental protection side, we take a minimalist approach in packaging, and limit our stock to room-temperature-stable products only to reduce energy cost in storage.

Selected Publications

  • Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115 J. Med. Chem. 2015, 58, 5599.
  • Discovery of Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor CC-223 J. Med. Chem. 2015, 58, 5323.
  • Use of core modification in the discovery of CC214-2, an orally available, selective inhibitor of mTOR kinase Bioorg. Med. Chem. Lett. 2013, 23, 1588.
  • Discovery and SAR exploration of a novel series of imidazo[4,5-b]pyrazin-2-ones as potent and selective mTOR kinase inhibitors Bioorg. Med. Chem. Lett. 2011, 21, 6793.
  • Methods of synthesis and purification of heteroaryl compounds, WO2011/053518.
  • mTor kinase inhibitors for oncology indications and diseases associated with the mTor/PI3K/Akt pathway, WO2010/062571.
  • Aminotriazolopyridines and their use as kinase inhibitors, WO2010/027500.
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AbovChem LLC has not listed any services.

Synthetic Building Blocks and Intermediates
Price on request

Chemical building blocks (~8,000) for medicinal chemistry.

Chemical building blocks (~8,000) for medicinal chemistry.

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Chemical Reference Standards
Price on request

Reference Tool Compounds (~6,000) for target validation.

Reference Tool Compounds (~6,000) for target validation.

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Chemical Synthesis
Price on request

Custom synthesis of chemical probes, reference tool compounds, and focus libraries.

Custom synthesis of chemical probes, reference tool compounds, and focus libraries.

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Chemistry and Materials
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Synthetic Chemistry
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Analytical Chemistry Services
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2018-09-28 18:27:33 -0400

Net Promoter Score of 10 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 9,
September 28, 2018

Positive review received for Chemical Synthesis:

"Working with Branden has been a great experience. He is very knowledgeable about synthesis of custom materials, formulating and purification of organics. He is a clear communicator and sends detailed updates with progress reports and creative solutions to any road blocks that may be causing delays. I'd definitely work with Branden again."

2018-06-12 14:12:00 -0400

Net Promoter Score of 10 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2018-06-07 13:59:10 -0400

Net Promoter Score of 9 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 9, satisfaction with timeliness: 9.
2018-06-07 13:41:24 -0400

Net Promoter Score of 10 received for Chemical Synthesis.

2018-05-30 20:48:32 -0400

Net Promoter Score of 10 received for Chemical Reference Standards.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2018-05-25 13:50:08 -0400

Net Promoter Score of 10 received for Chemistry and Materials.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2018-04-23 14:08:47 -0400

Net Promoter Score of 7 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 7, satisfaction with timeliness: 7.
March 21, 2018

Positive review received for Chemical Synthesis:

"I'm very satisfied with the quality of the compound AbovChem synthesized for us and their reasonable price for the service."

2018-03-19 10:59:13 -0400

Net Promoter Score of 10 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2018-03-15 22:23:51 -0400

Net Promoter Score of 10 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2018-01-08 15:28:03 -0500

Net Promoter Score of 7 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 9, satisfaction with timeliness: 7.
2017-12-19 15:14:45 -0500

Net Promoter Score of 10 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2017-12-14 17:09:03 -0500

Net Promoter Score of 10 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 7.
2017-12-05 17:35:58 -0500

Net Promoter Score of 10 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2017-11-06 22:46:51 -0500

Net Promoter Score of 10 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2017-09-11 14:26:08 -0400

Net Promoter Score of 10 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2017-07-17 19:30:49 -0400

Net Promoter Score of 10 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2017-05-15 16:37:19 -0400

Net Promoter Score of 8 received for Chemical Synthesis.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 8.
March 16, 2017

Positive review received for Chemical Synthesis:

"AbovChem, specifically Branden Lee, have been very flexible and have actively worked with us when we have needed to change the scope. The turnaround time for responses and proposals has been extremely rapir, usually within 1-2 hours."

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