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Ablab

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Utrecht, NL

About Ablab

Divison of: Utrecht University

AbLab: Your partner for Native Protein MS services
April 2014

AbLab, a service unit within the Heck lab of the Utrecht University, provides state of the art Native MS services. Due to this unique position AbLab has access to the latest insights, innovations, methodology and instrumentation for providing... Show more »

AbLab: Your partner for Native Protein MS services
April 2014

AbLab, a service unit within the Heck lab of the Utrecht University, provides state of the art Native MS services. Due to this unique position AbLab has access to the latest insights, innovations, methodology and instrumentation for providing mass spectrometry services.

Native MS is emerging as a powerful technique for the characterization of antibodies, especially antibody mixtures, and in principle all therapeutic proteins. It provides the identity and accurate relative quantitative data of species in a mixture and complements, in many cases supersedes, conventional techniques such as cation exchange chromatography (CEX).

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Our Services (5)


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Native Mass Spectrometry

Native Mass Spectrometry
Price on request

Native Mass Spectrometry (Native MS) is an emerging powerful technique to analyse the mass of intact proteins and their assemblies. The key feature that makes native MS unique is the retention of molecular non-covalent interactions during the ionization process and the subsequent mass analysis. This feature of Native MS allows us... Show more »

Native Mass Spectrometry (Native MS) is an emerging powerful technique to analyse the mass of intact proteins and their assemblies. The key feature that makes native MS unique is the retention of molecular non-covalent interactions during the ionization process and the subsequent mass analysis. This feature of Native MS allows us to determine the complex stoichiometry, interaction between two protein partners and thus sample composition and purity. Ablab has experience with characterization of antibodies, especially antibody mixtures. Native MS provides the identity and accurate relative quantitative data of species in a mixture and complements, in many cases supersedes conventional techniques such as cation exchange chromatography (CEX).

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Specialty Mass Spectrometry Methods

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Mass Spectrometry

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Spectroscopy

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Imaging & Spectroscopy

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Dominique Hagemans

Research Technician

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