Ab Studio Inc.
About Ab Studio Inc.
Ab Studio Inc. is a start-up Biotech founded in Feb., 2017 in bay area, USA. Founder and leading scientist have extensive expertise in the field of therapeutic antibody discovery, lead selection, engineering, humanization and optimization.
Ab Studio aims to support the whole therapeutic antibody R&D... Show more »
Ab Studio Inc. is a start-up Biotech founded in Feb., 2017 in bay area, USA. Founder and leading scientist have extensive expertise in the field of therapeutic antibody discovery, lead selection, engineering, humanization and optimization.
Ab Studio aims to support the whole therapeutic antibody R&D field with 1) novel technology platforms on making bispecific and internalization antibodies 2) high quality antibody discovery, engineering, humanization and optimization services 3) CMC and IND-filing partnering.
We look forward to working together with our CMC partner and IND filing collaborator to provide our clients the best pre-clinical stage therapeutic antibody development service.
Our Services (14)
CMC Regulatory Compliance Support
Antibody Optimization
- Detailed sequence analysis and 3D structure modeling
- Identification of the best human germline sequence templates, grafting the rodent or rabbit antibody CDR regions into the human antibody frameworks
- Identifying back-mutations and remove “hot spots” with developability issues
- High throughput lead selection and... Show more »
- Detailed sequence analysis and 3D structure modeling
- Identification of the best human germline sequence templates, grafting the rodent or rabbit antibody CDR regions into the human antibody frameworks
- Identifying back-mutations and remove “hot spots” with developability issues
- High throughput lead selection and evaluation
- Efficient lead preparation for research purpose in house (up to 20mg), CMC level protein preparation at the facility of our CMC partner
Antibody Discovery
- Monoclonal Antibody discovery service: hybridoma and phage display
- Antigen design via bioinformatics and computer aided design
- Antibody development via hybridoma and/or phage display technology
- Screening mAb clones for high affinity, high expression, good efficacy and good developability
- Antigen design via bioinformatics and computer aided design
- Bispecific antibody... Show more »
- Monoclonal Antibody discovery service: hybridoma and phage display
- Antigen design via bioinformatics and computer aided design
- Antibody development via hybridoma and/or phage display technology
- Screening mAb clones for high affinity, high expression, good efficacy and good developability
- Antigen design via bioinformatics and computer aided design
- Bispecific antibody discovery service
- Apply “knob into hole” plus common light chain technology for bispecific antibody development
- Use Ab Studio’s unique methodology to screen common light chain
- Apply computer aided design to engineer the two arms of a bi-specifc antibody for better purification efficacy
- Apply “knob into hole” plus common light chain technology for bispecific antibody development
- Internalization antibody discovery service
Antibody Humanization
- Detailed sequence analysis and 3D structure modeling
- Identification of the best human germline sequence templates, grafting the rodent or rabbit antibody CDR regions into the human antibody frameworks
- Identifying back-mutations and remove “hot spots” with developability issues
- High throughput lead selection and... Show more »
- Detailed sequence analysis and 3D structure modeling
- Identification of the best human germline sequence templates, grafting the rodent or rabbit antibody CDR regions into the human antibody frameworks
- Identifying back-mutations and remove “hot spots” with developability issues
- High throughput lead selection and evaluation
- Efficient lead preparation for research purpose in house (up to 20mg), CMC level protein preparation at the facility of our CMC partner
IND/NDA/BLA Submission
Investigational New Drug/New Drug Application Submission
We collaborate with our partner Data-revive for IND filing
- We will discuss with specialists at Data-revive for the need of IND filing during the whole process of preclinical stage therapeutic antibody development
- We will write antibody discovery, lead selection, antibody humanization and optimization report to support our clients to file IND
We collaborate with our partner Data-revive for IND filing
- We will discuss with specialists at Data-revive for the need of IND filing during the whole process of preclinical stage therapeutic antibody development
- We will write antibody discovery, lead selection, antibody humanization and optimization report to support our clients to file IND
Chemistry, Manufacturing and Controls (CMC)
Antibody Development Service (CMC)
- We partner with Mab-Venture Biopharma to provide our clients with high quality CMC services.
- We can also work with CMC facilities chosen by our clients for lead therapeutic antibody manufacture protcol design and process trouble shooting
Antibody Development Service (CMC)
- We partner with Mab-Venture Biopharma to provide our clients with high quality CMC services.
- We can also work with CMC facilities chosen by our clients for lead therapeutic antibody manufacture protcol design and process trouble shooting
Project Management
Therapeutic Monoclonal Antibody (mAb) Development
Antibody Services
Formulation Services
Regulatory Affairs Services
Biology
Protein Services
Biochemistry & Molecular Biology
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Get info on this provider's capabilities without requesting a quote.Yue Liu
CEO
Ab Studio Inc. has not received any reviews.
Ab Studio Inc. has not received any endorsements.